| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
9.B.369.1.1 | The 4 TMS Strabismus2 (STB2), Van Gogh-like-1 (VANGL1)protein with 524 aas. It may function with retromer complexes (TC#s 9.A.3 and 9.A.63). Retromer controls planar polarity protein levels and asymmetric localization at intercellular junctions (Strutt et al. 2019). Planar cell polarity (PCP) plays critical roles in developmental and homeostatic processes. Membrane presentation of PCP complexes containing Van Gogh-like (VANGL) transmembrane proteins is central to PCP and can be directed by the scaffold protein scribble (SCRIB) (Almeida et al. 2023). | Eukaryota |
Metazoa, Chordata | STB2 of Homo sapiens |
|
9.B.369.1.2 | Van Gogh Protein of 789 aas and 4 N-terminal TMSs | Eukaryota |
Metazoa, Platyhelminthes | VANGL protein of Schistosoma japonicum |
|
9.B.369.1.3 | Uncharacterized protein of 702 aas and 4 TMSs | Eukaryota |
Metazoa, Platyhelminthes | UP of Fasciola hepatica (liver fluke) |
|
9.B.369.1.4 | Uncharacterized protein of 770 aas and 4 central TMSs. | Eukaryota |
Metazoa, Platyhelminthes | UP of Rodentolepis nana |
|
9.B.369.1.5 | Uncharacterized protein of 354 aas and 2 C-terminal TMSs | Eukaryota |
Metazoa, Platyhelminthes | UP of Protopolystoma xenopodis |
|
9.B.369.1.6 | Uncharacterized protein of 1085 aas and 5 TMSs, 1 N-terminal and 4 together in the central part of the protein. | Eukaryota |
Metazoa, Platyhelminthes | UP of Sparganum proliferum |