9.B.399. The Merozoite Surface Protein (MSP) Family
Members of the MSP family are present in Plasmodium falciparum. Some members of this family (MSP4 and MSP5) arose by gene duplication, They are encoded within a gene cluster arranged in the order msp4, msp5, msp2 and asl genes where Asl is an adenylosuccinate lyase (ASL), an enzyme involved in purine biosynthesis and salvage (Polson et al. 2005). Msp4 and Msp5 (both of 272 aas) have two TMSs, N- and C-terminal.