9.B.56 The Bacterial Disease Resistance and Oomycete Disease Susceptibility Protein, PIMP1 (PIMP1) Family 

These proteins are required for defense responses to Xanthomonas campestris pv. vesicatoria (Xcv). In heterologous systems, they confers resistance to bacterial pathogens such as Pseudomonas syringae pv. tomato but susceptibility to pathogenic oomycetes such as Hylaloperonospora parasitica when expressed in Arabidopsis thaliana or Capsicum annuum (Bell pepper) (Hong et al. 2008).  May be involved in the regulation of responses to bitoic and abiotic stresses (Hong and Hwang 2009).  These proteins belong to the DUF588 or MARVEL superfamily.  MARVEL domain-containing proteins are often found in lipid-associating proteins such as Occludin and MAL family proteins.