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1.A.115.  The Pore-forming NADPH-dependent 1-Acyldihydroxyacetone Phosphate Reductase (Ayr1) Family

The short-chain dehydrogenase-related protein Ayr1 forms an NADPH-regulated channel in lipid bilayers and in the outer mitochondrial membrane (Krüger et al. 2017). It conducts ions across the outer membrane (Checchetto and Szabo 2018).

References associated with 1.A.115 family:

Checchetto, V. and I. Szabo. (2018). Novel Channels of the Outer Membrane of Mitochondria: Recent Discoveries Change Our View. Bioessays 40: e1700232. 29682771
Krüger, V., T. Becker, L. Becker, M. Montilla-Martinez, L. Ellenrieder, F.N. Vögtle, H.E. Meyer, M.T. Ryan, N. Wiedemann, B. Warscheid, N. Pfanner, R. Wagner, and C. Meisinger. (2017). Identification of new channels by systematic analysis of the mitochondrial outer membrane. J. Cell Biol. 216: 3485-3495. 28916712