1.A.128.1.1
Short putative ORF10 protein of 38 aas and 1 N-terminal TMS. This protein has been shown to be a viroporin that is inhibited by Amantadine (Toft-Bertelsen et al. 2021). Amantadine blocks the ion channel activity of ORF10 (Toft-Bertelsen et al. 2021). See family description for details. A cell-based system combined with flow cytometry has been used to evaluate
antibody responses against SARS-CoV-2 transmembrane proteins in
patients with COVID-19 (Martin et al. 2022).
|
| Accession Number: | YP_009725255 |
|---|
| Protein Name: | YP_009725255.1 ORF10 protein [Severe acute respiratory syndrome coronavirus 2] |
|---|
| Length: | 39 |
|---|
| Molecular Weight: | |
|---|
| Species: | Severe acute respiratory syndrome coronavirus 2 [2697049] |
|---|
| Number of TMSs: | 1 |
|---|
| Substrate |
|
|---|
1: MGYINVFAFP FTIYSLLLCR MNSRNYIAQV DVVNFNLT