1.A.14.3.9 Lifeguard homologue, CG3814 of 244 aas and 7 TMSs. Knockdown of CG3814/LFG in Ddc-Gal4-expressing neurons diminishes its neuroprotective ability, and results in a shortened lifespan and loss of
climbing ability, phenotypes that are improved upon overexpression of the pro-survival Buffy (M'Angale and Staveley 2016).
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Accession Number: | Q6AWP0 |
Protein Name: | CG3814, isoform A |
Length: | 239 |
Molecular Weight: | 26654.00 |
Species: | Drosophila melanogaster (Fruit fly) [7227] |
Number of TMSs: | 7 |
Substrate |
ion |
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1: MSSDNHFQYD AEADKSFAFD DQSIRKGFIR KVYLILMCQL LITFGFVSVF TFSKASQEWV
61: QKNPALFWIA LAVLIVTMIC MACCESVRRK TPLNFIFLFL FTVAESFLLG MVAGQFEADE
121: VLMAVGITAA VALGLTLFAL QTKYDFTMCG GVLVACLVVF IIFGIIAIFI PGKVIGLVYA
181: SLGALLFSVY LVYDTQLMLG GNHKYSISPE EYIFAALNLY LDIINIFMYI LTIIGLSRN