TCDB is operated by the Saier Lab Bioinformatics Group

1.A.145.  The gp120 Viroporin (gp120-VP) Family

This family has been examined, first, showing that its characterized member is a  small transmembrane protein of 100 aas and 1 centrally located TMS (residues 45 - 69). Second, it has been shown to have ion channel activity (Basu et al. 2023). Third, its 3-D transmembrane structure has been predicted using alpha-fold.