1.B.14.1.27
Iron(III) dicitrate transport protein, FecA1: iron dicitrate uptake receptor of 767 aas. Regulated by the ferric uptake regulator transcription factor, Fur (van Vliet et al. 2002) in response to iron availability (Danielli et al. 2009). Involved in iron deficiency anemia in children (Kato et al. 2017).
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| Accession Number: | D7FE37 |
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| Protein Name: | Iron(III) dicitrate transport protein (FecA) |
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| Length: | 767 |
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| Molecular Weight: | 87599.00 |
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| Species: | Helicobacter pylori (strain B8) [693745] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Cell outer membrane1 |
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| Substrate |
iron(3+), citrate salt |
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1: MKRILVFLAV LSHSAHAVKT HNLERVEASG VANDKEAPLS WRSKEVRNYM GSRTVISNKQ
61: LTKSANQSIE EALQNVPGVH IRNSTGIGAV PSISIRGFGA GGPGHSNTGM ILVNGIPIYV
121: APYVEIGTVI FPVTFQSVDR ISVTKGGESV RYGPNAFGGV INIITKGIPT NWESQVSERT
181: TFWGKSENGG FFNQNSKNID KSLVNNMLFN TYLRTGGMMN KHFGIQAQVN WLKGQGFRYN
241: SPTNIQNYLL DSLYQINDSN KITAFFQYYS YFLTDPGSLG IAAYNENRFQ NNRPNNDKSG
301: RAKRWGAVYQ NFFGDTDRVG GDFTFSYYGH DMSRDFKFDS NYLNVNTNPK LGPVYTDQNY
361: PGFFIFDHLR RYVMNAFEPN LNLVVNTNKV KQTFNVGMRF MTMDMFIRSD QSTCEKSDII
421: DGVCHMPPYV LSKKPSNNQE MFNNYTAVWL SDKIELFDSK LVITPGLRYT FLNYNNKEPE
481: KHDFSVWNIT KKRQNEWSPA LNIGYKPMEN WIWYANYRRS FIPPQHTMLG ITRTNYNQIF
541: NEIEVGQRYS YKNLLSFNTN YFVIFANRYY AGGYSPQPIN ARSQGVELEL YYAPIRGLQF
601: HVAYTYIDAR ITSNADDIAY YFTGIVNKPF DIKGKRLPYV SPNQFIFDMM YTYKHTTFGI
661: SSYFYSRAYS SMLNQAKSQT VCLPLNPEYT GGLEYGCNSV GLLPLYFVLN VQVSSVLWQS
721: GRHKITGSLQ INNLFNMKYY FRGIGTSPTG REPAPGRSIT AYLNYEF