1.G.22 The Cytomegalovirus (Human Herpesvirus 5)Glycoprotein gO (gO) Family
Feng and Jia 2016 described the molecular mechanisms of glycoprotein-induced fusion and entry of herpesviruses. gO or gL in part serves this function in Cytomegalovirus. The heterodimer, glycoprotein H-glycoprotein L, is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL
References associated with 1.G.22 family:
Feng, D. and R. Jia. (2016). [Molecular Mechanism of Glycoprotein-induced Cell-Cell Fusion of Herpesviruses]. Bing Du Xue Bao 32: 101-107. 27295891
Yue, Y., S.S. Zhou, and P.A. Barry. (2003). Antibody responses to rhesus cytomegalovirus glycoprotein B in naturally infected rhesus macaques. J Gen Virol 84: 3371-3379. 14645918