TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.G.9.1.1









HERV-W_7q21.2 provirus ancestral Env polyprotein (ENV-W; gPr73; enverin; syncytin-1, HERV-7q envelope protein) (Blond et al., 1999; Mi et al., 2000).  This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. It may induce fusion through binding of SLC1A4 and SLC1A5 (Blond et al. 2000; Lavillette et al. 2002; Lavillette et al. 2002; Sugimoto et al. 2013.

Eukaryota
Metazoa
HERV-W_7q21.2 of Homo sapiens (Q9UQF0)
1.G.9.1.2









Syncytin 2 of 538 aas.  Syncytins maintain cell-cell fusogenic activity based on ENV: gene-mediated viral cell entry but promote fusion of various cells during development in humans (Soygur and Sati 2016).

Eukaryota
Metazoa
Syncytin 2 of Homo sapiens
1.G.9.2.1









Envelope glycoprotein, Env

Viruses
Retroviridae
Env of porcine endogenous retrovirus A
1.G.9.2.2









The human T-lymphotropic virus type 1 (HTLV-1) glycoprotein gp21 of 121 aas and containing the N-terminal 25 aa fusion peptide with a single TMS.

Viruses
Retroviridae
gp21 of the human T-lymphotropic virus type 1 (HTLV-1)