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| Accession Number: | Q9WVC8 |
| Protein Name: | SLC26A3 aka DRA |
| Length: | 757 |
| Molecular Weight: | 83590.00 |
| Species: | Mus musculus (Mouse) [10090] |
| Number of TMSs: | 14 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | chloride, hydrogencarbonate |
Cross database links:
| RefSeq: | NP_067328.1 |
|---|---|
| Entrez Gene ID: | 13487 |
| Pfam: | PF01740 PF00916 |
| KEGG: | mmu:13487 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0015297
F:antiporter activity
GO:0008271
F:secondary active sulfate transmembrane tran...
GO:0008272
P:sulfate transport
GO:0055085
P:transmembrane transport
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References (2)[1] “Mouse down-regulated in adenoma (DRA) is an intestinal Cl(-)/HCO(3)(-) exchanger and is up-regulated in colon of mice lacking the NHE3 Na(+)/H(+) exchanger.” Melvin J.E.et.al. 10428871 [2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334
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| Structure: | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MIEAIGNQYV VARPVYSTKT FGEEFKKTHR HHKTFLDHLK GCCSCSSQKA KKIALSLFPI 61: ASWLPAYKIK EWLLSDIVSG ISTGLVAVLQ GLAFALLVNI PPAYGLYAAF FPVITYFFLG 121: TSRHISVGPF PVLSMMVGVV VTRVVSDPNA SSELSSSSTE NDSFIEEKVM VAASVTVLSG 181: IIQLLLGVLQ VGFVVIYLSE SLISGFTTAA AIHVLVSQLK FMLQLPVPAY SDPFSIFKVL 241: ESVFTQIQKT NIADLVTSVI ILVVVFVFKE INQRYRSKLP VPIPIELIMT VIATGVSYGC 301: NFEDRFGVAV VGNMSLGFQP PITPSVEVFQ DTIGDSFGIA IVGFAVAFSV ASVYSLKYDY 361: PIDGNQELIA LGVSNIFTGA FKGFAGSTAL SRSGVQESTG GKTQVAGLLS AVIVLIVIVA 421: IGFLLQPLQK SVLAALALGN LKGMLMQFAE IGRLWKKDKY DCLIWIMTFI FAIVLGLGLG 481: LAASVAFQLL TIVFRTQFPK CSTLANVGRS NIYKNKKNYA EVYEPEGVKI FRCPSPIYFA 541: NIGFFKQKLI DAVGFSPLRI LRKRNKALKK IRKLQKRGLI QMTPKGFICT SDGFKDSDEE 601: LDNNQIEELD QPINTTDLPF DIDWNGDLPL NITIPKISLH SLILDFSAVS FLDVSSMRGL 661: RTILQEFIRI KVDVYIVGTD DDFIDKLARC EFFDDEVTDS IFFLTIHDAI LHILMKKDYS 721: TSKFNSSQEK ERKFDFTINT NGGLRNRECQ VPVETKF