2.A.53.4.2
Sulfate transporter, Rv1739c (Zolotarev et al. 2008). Its STAS domain binds guanine nucleotides as shown by x-ray chrystalography (PDB# 2KLN; Sharma et al. 2011; Sharma et al. 2012). Sulfate uptake by Rv1739c requires CysA
and its associated sulfate permease activity, and suggest that Rv1739c may be a CysTWA-dependent
sulfate transport protein (Sharma et al. 2012). Sulfate uptake by Rv1739c requires CysA
and its associated sulfate permease activity, and suggest that Rv1739c may be a CysTWA-dependent
sulfate transport protein (Zolotarev et al. 2008).
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| Accession Number: | P71997 |
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| Protein Name: | Probable sulfate transporter Rv1739c/MT1781 |
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| Length: | 560 |
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| Molecular Weight: | 59367.00 |
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| Species: | Mycobacterium tuberculosis [1773] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
sulfate |
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1: MIPTMTSAGW APGVVQFREY QRRWLRGDVL AGLTVAAYLI PQAMAYATVA GLPPAAGLWA
61: SIAPLAIYAL LGSSRQLSIG PESATALMTA AVLAPMAAGD LRRYAVLAAT LGLLVGLICL
121: LAGTARLGFL ASLRSRPVLV GYMAGIALVM ISSQLGTITG TSVEGNEFFS EVHSFATSVT
181: RVHWPTFVLA MSVLALLTML TRWAPRAPGP IIAVLAATML VAVMSLDAKG IAIVGRIPSG
241: LPTPGVPPVS VEDLRALIIP AAGIAIVTFT DGVLTARAFA ARRGQEVNAN AELRAVGACN
301: IAAGLTHGFP VSSSSSRTAL ADVVGGRTQL YSLIALGLVV IVMVFASGLL AMFPIAALGA
361: LVVYAALRLI DLSEFRRLAR FRRSELMLAL ATTAAVLGLG VFYGVLAAVA LSILELLRRV
421: AHPHDSVLGF VPGIAGMHDI DDYPQAKRVP GLVVYRYDAP LCFANAEDFR RRALTVVDQD
481: PGQVEWFVLN AESNVEVDLT ALDALDQLRT ELLRRGIVFA MARVKQDLRE SLRAASLLDK
541: IGEDHIFMTL PTAVQAFRRR