| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
8.A.98.1.1 | The dimeric fly 14-3-3zeta protein of 248 aas modulates as a negative regulator to control the activity of the Slowpoke calcium-dependent potassium channel (dSlo) by interacting with the dSlo binding protein, Slob (Zhou et al. 2003). | Eukaryota |
Metazoa, Arthropoda | 14.3.3zeta of Drosophila melanogaster (Fruit fly) |
|
8.A.98.1.2 | 14-3-3zeta/delta protein of 245 aas, an adapter protein implicated in the regulation of a large number of signaling systems and transport proteins. It binds to its partners, often by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the target partner protein (Tsuruta et al. 2004; Gu et al. 2006). | Eukaryota |
Metazoa, Chordata | 14-3-3 of Homo sapiens |
|
8.A.98.1.3 | 14-3-3 protein of 262 aas. | Eukaryota |
Apicomplexa | 14-3-3 of Plasmodium falciparum |
|
8.A.98.1.4 | 14-3-3ε protein of 169 aas | Eukaryota |
Ciliophora | 14-3-3ε of Tetrahymena thermophila |
|
8.A.98.1.5 | Uncharacterized protein of 212 aas. | Eukaryota |
Metazoa, Nematoda | UP of Ascaris suum (Pig roundworm) (Ascaris lumbricoides) |
|
8.A.98.1.6 | 14-3-3 protein of 363 aas. | Eukaryota |
Fungi, Ascomycota | 14-3-3 protein of Glarea lozoyensis |
|
8.A.98.1.7 | 14-3-3 homologue of 233 aas. | Eukaryota |
Foraminifera | 14-3-3 of Reticulomyxa filosa |
|
8.A.98.1.8 | 14-3-3 protein, GF14λ, ATF1, RCI2, of 248 aas | Eukaryota |
Viridiplantae, Streptophyta | 14-3-3 protein of Arabidopsis thaliana |
|
8.A.98.1.9 | 14-3-3 theta (YWHAQ) of 245 aas and 0 TMSs. It is an adapter protein implicated in the regulation of several general and specialized signaling pathways. It binds
to a large number of partners, usually by recognition of a
phosphoserine or phosphothreonine motif. Binding generally results in
the modulation of the activity of the binding partner (Asih et al. 2022). | Eukaryota |
Metazoa, Chordata | YWHAQ of Homo sapiens |
|
8.A.98.1.10 | 14-3-3 protein epsilon , 14-3-3ε, of 255 aas and 0 TMSs. It positively regulates phosphorylated protein HSF1 (Q00613; 529 aas, 0 TMSs) nuclear export to the cytoplasm (Wang et al. 2003).
| Eukaryota |
Metazoa, Chordata | 14-3-3ε adaptor protein of Homo sapiens |
|
8.A.98.1.11 | 14-3-3 protein gamma, 14-3-3γ or YWHAG, of 247 aas and 0 TMSs. It is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. It binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (Jin et al. 2006). The 14-3-3gamma isoform binds to and regulates the localization of endoplasmic reticulum (ER) membrane protein TMCC3 for the reticular network of the ER (Suhda et al. 2023). | Eukaryota |
Metazoa, Chordata | 14-3-3γ of Homo sapiens |
|
8.A.98.2.1 | Uncharacterized protein of 294 aas and 1 N-terminal TMS. | Bacteria |
Bacillota | UP of Streptococcus iniae |