9.B.311.2.4
Translocating chain-associated membrane protein 2, TRAM2, of 370 aas and 3 TMSs. It interacts with SERCA2b (Stefanovic et al. 2004). TRAM2 , a membrane
protein containing a putative ceramide-interacting domain. It plays a role in membrane insertion of integral membrane proteins, influencing their topologies (Chen et al. 2016).
|
| Accession Number: | Q15035 |
|---|
| Protein Name: | Translocating chain-associated membrane protein 2 |
|---|
| Length: | 370 |
|---|
| Molecular Weight: | 43328.00 |
|---|
| Species: | Homo sapiens (Human) [9606] |
|---|
| Number of TMSs: | 7 |
|---|
| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
|
|---|
1: MAFRRRTKSY PLFSQEFVIH NHADIGFCLV LCVLIGLMFE VTAKTAFLFI LPQYNISVPT
61: ADSETVHYHY GPKDLVTILF YIFITIILHA VVQEYILDKI SKRLHLSKVK HSKFNESGQL
121: VVFHFTSVIW CFYVVVTEGY LTNPRSLWED YPHVHLPFQV KFFYLCQLAY WLHALPELYF
181: QKVRKEEIPR QLQYICLYLV HIAGAYLLNL SRLGLILLLL QYSTEFLFHT ARLFYFADEN
241: NEKLFSAWAA VFGVTRLFIL TLAVLAIGFG LARMENQAFD PEKGNFNTLF CRLCVLLLVC
301: AAQAWLMWRF IHSQLRHWRE YWNEQSAKRR VPATPRLPAR LIKRESGYHE NGVVKAENGT
361: SPRTKKLKSP