TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
9.B.385.1.1









The TMEM39A or SUSR2 protein of 488 aas and 8 TMSs in a 4 + 2 + 2 TMS arrangement.  It plays a role in cell physiology and pathology (see the family description).  A cell penetrating peptide has been derived from it (see TC# 1.D.124). The ER-localized TMEM39A/SUSR2 regulates autophagy by controlling trafficking of the PtdIns(4)P phosphatase SAC1 (Miao et al. 2020).

Eukaryota
Metazoa
TMEM39a of Homo sapiens
9.B.385.1.2









Uncharacterized protein of 442 aas and 8 TMSs in a 4 + 2 + 2 TMS arrangement.

Eukaryota
Choanoflagellata
UP of Salpingoeca rosetta
9.B.385.1.3









Uncharacterized protein of 417 aas and 8 TMSs in a 4 + 2 + 2 TMS arrangement.

Eukaryota
Discosea
UP of Acanthamoeba castellanii
9.B.385.1.4









Membrane protein of 8 TMSs in a 4 + 2 + 2 TMS arrangement.

Eukaryota
Ciliophora
Membrane protein of Tetrahymena thermophila
9.B.385.1.5









Uncharacterized protein (fragment?) of 356 aas and 6 - 8 TMSs.

Eukaryota
Oomycota
UP of Aphanomyces euteiches