| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
8.A.132.1.1 | The Supressor of Lurcher 1, SOL1, or interferon alpha/beta receptor 1, IFNAR1, of 557 aas and 2 TMSs, one N-terminal and one C-terminal. SOL1 proteins regulate ionotropic glutamate receptor desensitization (Walker et al. 2006). SOL1 is an accessory protein requlred for glutamate-gated currents by Glr-1 (Zheng et al. 2004). This protein has an internal duplication and belongs to the FN3 superfamily. Its trafficking and signaling have been reported (Zanin et al. 2020). | Eukaryota |
Metazoa, Chordata | SOL1 of Caenorhabditis elegans |
|
8.A.132.1.2 | Uncharacterized protein of 897 aas and 2 TMSs, N-terminal and in the middle of the protein. | Eukaryota |
Metazoa, Chordata | UP of Branchiostoma belcheri |
|
8.A.132.1.3 | Uncharacterized protein of 621 aas and 2 TMSs, one N-terminal and one in the middle of the protein. | Eukaryota |
Metazoa, Chordata | UP of Fundulus heteroclitus |
|
8.A.132.1.4 | Interleukin-22 receptor subunit alpha-1-like protein of 253 aas and 1 N-terminal TMS. This protein, in contrast to the homologues with TC#s 8.Al47.2.1 - 2.3, has a single repeat unit rather than a duplicated structure. | Eukaryota |
Metazoa, Chordata | Interlleukin-22 receptor of Xenopus laevis |
|
8.A.132.1.5 | Uncharacterized proteinof 871 aas and 3 apparent TMSs, 2 N-terminal and one towards the C-terminus of the protein. | Eukaryota |
Metazoa, Chordata | UP of Ciona intestinalis |
|
8.A.132.1.6 | Interferon gamma receptor 2 of 349 aas and 1 TMS | Eukaryota |
Metazoa, Chordata | Interferon receptor of Heterocephalus glaber (naked mole-rat) |
|
8.A.132.1.7 | Interleukin-20 receptor subunit beta isoform X1 of 403 aas and 6 TMSs in a 3 + 3 TMS arrangement. | Eukaryota |
Metazoa, Chordata | Interleukin receptor of Ursus maritimus (polar bear) |
|
8.A.132.1.8 | Interleukin-22 receptor subunit alpha-1 of 581 aas and 1 TMS | Eukaryota |
Metazoa, Chordata | Interleukin receptor of Panthera tigris altaica (Amur tiger) |
|
8.A.132.1.9 | Interferon lambda receptor 1-like isoform X2 of 556 aas and 2 TMSs, one N-terminal and one central. | Eukaryota |
Metazoa, Chordata | Interferon receptor of Oncorhynchus mykiss (rainbow trout) |
|
8.A.132.1.10 | Interferon gamma receptor 1 of 437 aas and 1 TMS. | Eukaryota |
Metazoa, Chordata | Interferon receptor of Amazona aestiva (blue-fronted amazon) |
|
8.A.132.1.11 | Uncharacterized protein of 571 aas and 1 N-terminal TMS | Eukaryota |
Metazoa, Chordata | UP of Maylandia zebra (zebra mbuna) |
|
8.A.132.1.12 | Interferon lambda receptor 1 isoform X1 of 504 aas and 1 TMS. | Eukaryota |
Metazoa, Chordata | Interferon receptor of Manis javanica (Malayan pangolin) |
|
8.A.132.1.13 | Interleukin-10 receptor, subunits alpha/beta. The alpha subunit has 578 aas with 2 TMSs, one N-terminal and the other at ~ residue 245 and the beta subunit is of 325 aas, with 2 TMSs, one N-terminal and the other at ~ residue 230. A cryoEM structure is available (Cai et al. 2022). | Eukaryota |
Metazoa, Chordata | Interleukin-10 of Homo sapiens |
|
8.A.132.2.1 | Tissue factor F3 of 295 aas and 2 TMSs, N- and C-terminal. It initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade (Bogdanov et al. 2003). | Eukaryota |
Metazoa, Chordata | TF3 of Homo sapiens |