| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
8.A.6.1.1 | Cold-sensitive fermentation (CSF1) protein of 2985 aas. It is a tube-forming lipid transport protein which provides phosphatidylethanolamine for glycosylphosphatidylinositol (GPI) anchor synthesis in the endoplasmic reticulum (Toulmay et al. 2022). It is required for the glucose and other nutrients uptake at low temperature (Tokai et al. 2000). | Eukaryota |
Fungi, Ascomycota | CSF1 of Saccharomyces cerevisiae |
|
8.A.6.1.2 | Bridge-like lipid transfer protein family member 1 C-terminal domain-containing protein, Lpd-1, of 4018 aas and at least one N-terminal TMS, but several additional potential TMSs. It is a tube-forming lipid transport protein which provides phosphatidylethanolamine for glycosylphosphatidylinositol (GPI) anchor synthesis in the endoplasmic reticulum. It also plays a role in endosomal trafficking and endosome recycling, and is involved in the actin cytoskeleton and cilia structural dynamics (Kane et al. 2019). It acts as regulator of phagocytosis (Jeng et al. 2019). | Eukaryota |
Metazoa, Nematoda | Lpd-1 of Caenorhabditis elegans |
|
8.A.6.1.3 | Bridge-like lipid transfer protein family member 1, Bltp1, of 5005 aas with one N-terminal TMS plus possibly additional TMSs elsewhere. It is a tube-forming lipid transport protein which provides phosphatidylethanolamine for glycosylphosphatidylinositol (GPI) anchor synthesis in the endoplasmic reticulum, and it plays a role in endosomal trafficking and endosome recycling. It may also be involved in the actin cytoskeleton and cilia structural dynamics (Kane et al. 2019) while also acting as a regulator of phagocytosis (Jeng et al. 2019). | Eukaryota |
Metazoa, Chordata | Bltp1 of Homo sapiens |